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Immunohistochemistry of paraffin-embedded human testis using FNab09523(WRAP53 antibody) at dilution of 1:100 -
IP Result of anti-WRAP53 (IP:FNab09523, 4ug; Detection:FNab09523 1:300) with HeLa cells lysate 2480ug. -
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab09523(WRAP53 antibody) at dilution of 1:300
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SKU:FNab09523
anti- WRAP53 antibody
anti- WRAP53 antibody
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anti- WRAP53 antibody
Product Name
WRAP53 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs(scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.
IMMUNOGEN INFORMATION
Immunogen
WD repeat containing, antisense to TP53
Synonyms
FLJ10385, TCAB1, WDR79, WRAP53
Observed MW
72 kDa
APPLICATION
Tested Application
ELISA, WB, IHC, IP
Recommended Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:1000
UNIPROT INFORMATION
UniProt ID
IMAGES
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