anti- XPG antibody

anti- XPG antibody

Product Name

XPG antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair(NER). It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light [PMID:22815677].

IMMUNOGEN INFORMATION

Immunogen

excision repair cross-complementing rodent repair deficiency, complementation group 5

Synonyms

COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC

Observed MW

200 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:200-1:2000; IF: 1:20-1:200; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

P28715 

IMAGES