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Immunohistochemistry of paraffin-embedded human colon cancer using FNab09566(YME1L1 antibody) at dilution of 1:100 -
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab09566(YME1L1 antibody) at dilution of 1:300
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SKU:FNab09566
anti- YME1L1 antibody
anti- YME1L1 antibody
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anti- YME1L1 antibody
Product Name
YME1L1 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
YME1L1(ATP-dependent zinc metalloprotease) is also named as FTSH1, YME1L,Meg-4,PAMP. YME1L1 plays a phylogenetically conserved role in mitochondrial protein metabolism.It also ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. YME1L1 can prevent mitochondrial DNA inserting into nuclear. It has 3 isoforms produced by alternative splicing with the molecular weight of 86 kDa, 80 kDa and 76 kDa.
IMMUNOGEN INFORMATION
Immunogen
YME1-like 1
Synonyms
FTSH, FTSH1, Meg 4, MEG4, PAMP, YME1 like 1, YME1 like protein 1, YME1L, YME1L1
Observed MW
86 kDa, 60 kDa
APPLICATION
Tested Application
ELISA, WB, IHC, IF
Recommended Dilution
WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:50-1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
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