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Immunohistochemistry of paraffin-embedded human brain using FNab09572(YTHDF1 antibody) at dilution of 1:100 -
IP Result of anti-YTHDF1 (IP:FNab09572, 4ug; Detection:FNab09572 1:1000) with mouse brain tissue lysate 2640ug. -
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09572(YTHDF1 antibody) at dilution of 1:500
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SKU:FNab09572
anti- YTHDF1 antibody
anti- YTHDF1 antibody
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anti- YTHDF1 antibody
Product Name
YTHDF1 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
Specifically recognizes and binds N6-methyladenosine(m6A)-containing mRNAs, and promotes mRNA translation efficiency(PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability(PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3(EIF3A or EIF3B) to facilitate translation initiation(PubMed:26046440).
IMMUNOGEN INFORMATION
Immunogen
YTH domain family, member 1
Synonyms
C20orf21, DACA 1, FLJ20391, YTH domain family protein 1, YTH domain family, member 1, YTHDF1
Observed MW
62 kDa
APPLICATION
Tested Application
ELISA, WB, IHC, IP
Recommended Dilution
WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
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