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Immunohistochemistry of paraffin-embedded human heart slide using FNab09629(ZFYVE19 Antibody) at dilution of 1:50 -
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09629(ZFYVE19 antibody) at dilution of 1:2000
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SKU:FNab09629
anti- ZFYVE19 antibody
anti- ZFYVE19 antibody
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anti- ZFYVE19 antibody
Product Name
ZFYVE19 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4(VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
IMMUNOGEN INFORMATION
Immunogen
zinc finger, FYVE domain containing 19
Synonyms
FLJ14840, MPFYVE, ZFYVE19
Observed MW
52 kDa
APPLICATION
Tested Application
ELISA, WB, IHC
Recommended Dilution
WB: 1:1000-1:10000; IHC: 1:20-1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
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