anti- Zinc-alpha-2-glycoprotein antibody

Product Name

Zinc-alpha-2-glycoprotein antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Zinc-alpha-2-glycoprotein(AZGP1) is a 41-kDa soluble protein normally found in body fluids, functions as a lipid mobilizing factor(PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex(MHC) antigens(PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors(PMID: 22625427).

IMMUNOGEN INFORMATION

Immunogen

alpha-2-glycoprotein 1, zinc-binding

Synonyms

AZGP1, ZA2G, ZAG, Zinc-alpha-2-glycoprotein, Zn alpha 2 glycoprotein, Zn alpha 2 GP, ZNGP1

Observed MW

41 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IF: 1:20-1:200; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P25311

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