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Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab09671(ZNF238 Antibody) at dilution of 1:50 -
IP result of anti-ZNF238 (FNab09671 for IP and Detection) with mouse cerebellum tissue. -
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab09671(ZNF238 antibody) at dilution of 1:1000
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SKU:FNab09671
anti- ZNF238 antibody
anti- ZNF238 antibody
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Product Name
ZNF238 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
ZNF238 is a member of the BTB/POZ-ZF protein family, which involve in development and cancer formation, for example BCL-6, PLZF, and HIC-1. It's a transcriptional repressor involve in myogenesis and brain development. By directly repressing the expression of two skeletal myogenesis inhibitors, ID2 and ID3, ZNF238 plays a key role in myogenesis. It can control cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Besides, ZNF238 involves in the organization of nuclear chromosomes, for its specific binding to the consensus DNA sequence that contains the E box core, and recruiting chromatin remodeling multiportein complex. ZNF238 proteins has apparent molecular masses of 60 and 48 kD. Specific binding is found for a 60-kDa band which corresponds to the full length of RP58 protein. In addition, a 48-kDa band, thought to be the truncated form 2 is detected(PMID: 9756912).
IMMUNOGEN INFORMATION
Immunogen
zinc finger protein 238
Synonyms
58 kDa repressor protein, C2H2 171, RP58, TAZ 1, TAZ1, Transcriptional repressor RP58, ZBTB18, ZFP238, zinc finger protein 238, Zinc finger protein C2H2 171, ZNF238
Observed MW
48 kDa
APPLICATION
Tested Application
ELISA, WB, IP, IHC
Recommended Dilution
WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
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