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Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab09761(ZWILCH Antibody) at dilution of 1:50 -
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09761(ZWILCH Antibody) at dilution of 1:500
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SKU:FNab09761
anti- ZWILCH antibody
anti- ZWILCH antibody
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anti- ZWILCH antibody
Product Name
ZWILCH antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:15824131).
IMMUNOGEN INFORMATION
Immunogen
Zwilch, kinetochore associated, homolog(Drosophila)
Synonyms
FLJ10036, FLJ16343, hZwilch, KNTC1AP, Protein zwilch homolog, ZWILCH
Observed MW
67 kDa
APPLICATION
Tested Application
ELISA, WB, IHC
Recommended Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
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