anti- CD3 ζ(Phospho-Tyr142) antibody

Embark on a journey into the world of T-cell receptor signaling with our Anti-CD3 ζ (Phospho-Tyr142) Polyclonal Antibody, now available in a convenient 100µg size. CD3 ζ, a crucial component of the T-cell receptor (TCR) complex, plays a central role in T-cell activation and immune response regulation.

Our meticulously developed polyclonal antibody, derived from rabbit hosts, offers exceptional sensitivity and versatility for various research applications, including Western blotting and flow cytometry. Whether you're investigating CD3 ζ phosphorylation dynamics or T-cell signaling pathways, this antibody's polyclonal nature allows recognition of multiple epitopes, enhancing its utility in diverse research contexts.

With 100µg at your disposal, you have a generous supply for multiple experiments, reducing the need for frequent reordering and ensuring the continuity of your research.

Explore the phosphorylation dynamics of CD3 ζ at Tyr142, a critical event in T-cell receptor signaling. Investigate the impact of CD3 ζ phosphorylation on downstream signaling cascades, immune cell activation, and immune response modulation. Our Anti-CD3 ζ (Phospho-Tyr142) Polyclonal Antibody empowers you to confidently advance your investigations, contributing to breakthroughs in immunology and immunotherapy research.

Whether you're an experienced immunologist or new to the field of T-cell receptor signaling, this antibody provides the precision, reliability, and quantity you need to propel your research forward. Uncover the mysteries of immune cell activation with this indispensable research tool.

Product Name

Phospho-CD3 ζ(Tyr142) antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive(T(-)/B(+)/NK(+) SCID) . A form of severe combined immunodeficiency(SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent

IMMUNOGEN INFORMATION

Immunogen

A synthesized peptide derived from human CD3 ζ(Phospho-Tyr142)

Synonyms

CD19 antigen; CD19 molecule; CD3 DELTA; CD3 EPSILON; CD3 GAMMA; CD3D; CD3D molecule; CD3E; CD3E molecule; CD3G; CD3G molecule;

Observed MW

17 kDa,21kDa,36kDa

APPLICATION

Tested Application

WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

P20963

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