anti- ABCC1 Antibody

Delve into the world of transport proteins with our Anti-ABCC1 Antibody, available in a 100µg size. ABCC1, a member of the ATP-binding cassette (ABC) transporter family, is known for its role in multidrug resistance and the efflux of various xenobiotics and drugs from cells. Understanding ABCC1 function is crucial for cancer research, pharmacology, and drug development.

Our meticulously designed antibody specifically targets ABCC1 with exceptional specificity and sensitivity, enabling precise detection and quantification in various research applications. Whether you are investigating drug resistance mechanisms in cancer cells, studying drug pharmacokinetics, or exploring the role of ABCC1 in xenobiotic transport, this antibody empowers you to make meaningful discoveries.

The 100µg size ensures you have ample supply for multiple experiments, reducing the need for frequent reorders and ensuring uninterrupted progress in your research. Each batch of our Anti-ABCC1 Antibody undergoes stringent quality control measures to guarantee consistent performance and reliability in your experiments. Join leading researchers in transporter biology and explore the diverse functions of ABCC1 with confidence.

Product Name

ABCC1 Antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.

IMMUNOGEN INFORMATION

Immunogen

ABCC1

Synonyms

ABC29; ABCC; ABCC1; ATP-binding cassette sub-family C member 1; ATP-binding cassette, sub-family C(CFTR/MRP), member 1; EC 3.6.3; EC 3.6.3.44; GS-X; Leukotriene C(4) transporter; LTC4 transporter; MRP1;multidrug resistance associated protein 1; multidrug resistance protein; multidrug resistance-associated protein 1; multiple drug resistance protein 1; multiple drug resistance-associated protein

Observed MW

173 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB 1:500-1:1000; IHC 1:50-1:100

UNIPROT INFORMATION

UniProt ID

P33527

IMAGES