anti- Caspase 2 antibody

Our Anti-Caspase 2 Antibody (Monoclonal, 100µg) is a specialized tool for researchers studying apoptosis and cell death mechanisms. Caspase 2, a member of the caspase family, has complex roles in regulating cell fate decisions. This monoclonal antibody is designed to specifically target Caspase 2, ensuring precision in your experiments.

The 100µg size provides an ample amount of antibody for multiple experiments, reducing the need for frequent restocking. Whether you're conducting Western blots, immunohistochemistry, or flow cytometry, this antibody consistently delivers high-quality results.

The monoclonal nature of this antibody ensures exceptional specificity and sensitivity, making it a preferred choice for discerning researchers. Its ability to recognize a single epitope with high affinity allows for accurate detection and quantification of Caspase 2.

Advance your apoptosis research with confidence using our Anti-Caspase 2 Antibody. Its reliability and precision will empower you to uncover critical insights into cell death pathways and their implications in biology and disease.

Product Name

Caspase 2 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.

IMMUNOGEN INFORMATION

Immunogen

Caspase 2

Synonyms

CASP 2, CASP2, Caspase 2, Caspase2, ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1

Observed MW

18, 32, 50 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:1000-1:6000

UNIPROT INFORMATION

UniProt ID

P42575

IMAGES