anti- Hsc70 antibody

anti- Hsc70 antibody

Product Name

Hsc70 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease. (21832061)

IMMUNOGEN INFORMATION

Immunogen

Hsc70

Synonyms

Heat shock 70 kDa protein 8, heat shock 70kDa protein 8, HSC54, Hsc70, HSC71, HSP71, HSP73, HSPA10, HSPA8, LAP1, NIP71

Observed MW

70 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:3000-1:20000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P11142

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