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FNab09844

anti- Huntingtin antibody

anti- Huntingtin antibody

$310.00 USD
$310.00 USD
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size

anti- Huntingtin antibody

Product Name

Huntingtin antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

HTT(huntingtin), also named as HD and IT15, belongs to the huntingtin family. HTT may play a role in microtubule-mediated transport or vesicle function. Defects in HTT are the cause of Huntington disease (HD) which is an autosomal dominant neurodegenerative disorder characterized by involuntary movements (chorea), general motor impairment, psychiatric disorders and dementia.

IMMUNOGEN INFORMATION

Immunogen

Huntingtin

Synonyms

HD, HD protein, HTT, Huntingtin, Huntington disease protein, IT15

Observed MW

348 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50-1:500; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P42858

IMAGES

 

Immunohistochemistry of paraffin-embedded rat brain tissue slide using FNab09844( Huntingtin antibody) at dilution of 1:200
Immunofluorescent analysis of (4% PFA) fixed human brain tissue using FNab09844 (Huntingtin antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
Various cells were subjected to SDS PAGE followed by western blot with FNab09844( Huntingtin Antibody) at dilution of 1:1000

 

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