anti- CXCR3 antibody

Our Anti-CXCR3 Polyclonal Antibody, available in a 100µg size, is a versatile and essential tool for researchers studying CXCR3, a chemokine receptor with critical roles in immune cell trafficking, inflammation, and cancer biology.

As a polyclonal antibody, it offers enhanced sensitivity and versatility, enabling you to delve deep into the molecular mechanisms underlying chemokine receptor signaling. We have rigorously validated the specificity of this antibody to ensure precise and reproducible results in your experiments.

Its compact size allows for a wide range of applications, from immunoprecipitation to flow cytometry. Whether you're unraveling the secrets of chemokine receptor function or exploring therapeutic targets, our Anti-CXCR3 Polyclonal Antibody is a trusted resource that will advance your scientific investigations. Trust in its quality to propel your research forward.

Product Name

CXCR3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

IMMUNOGEN INFORMATION

Immunogen

CXCR3

Synonyms

CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR

Observed MW

45 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P49682

IMAGES