anti- beta-Catenin antibody

Embark on a journey through the intricate world of cell adhesion and signaling with our Anti-Beta-Catenin Antibody (Monoclonal, 100µg). This antibody serves as your guiding light in deciphering the functions of Beta-Catenin, a multifunctional protein critical for cell-cell adhesion and Wnt signaling pathways.

Engineered for precision and rigor, this monoclonal antibody excels across various applications, from immunofluorescence to co-immunoprecipitation. Its high specificity and sensitivity ensure accurate and reproducible results, making it an indispensable tool in your cell biology and signal transduction research.

Beta-Catenin is a central player in the cadherin-mediated cell adhesion complex, as well as a key effector of the Wnt signaling cascade, influencing cell fate determination and development. With this monoclonal antibody in your research toolkit, you're well-equipped to delve into its functions, whether you're investigating its role in tissue morphogenesis, cancer biology, or its implications in regenerative medicine.

Navigate the path to scientific discovery by incorporating our Anti-Beta-Catenin Antibody (Monoclonal, 100µg) into your experiments today. Illuminate the intricate world of Beta-Catenin, paving the way for groundbreaking discoveries in the fields of cell biology, oncology, and beyond.

Product Name

beta-Catenin antibody

Size

100µg

Form

liquid

Purification

protein A+G purified

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

catenin(cadherin-associated protein), beta 1, 88kDa

Synonyms

b cat, Beta catenin, beta-Catenin, Catenin beta 1, CTNNB, CTNNB1, PRO2286, β catenin, β-catenin

Observed MW

90 kDa

APPLICATION

Tested Application

ELISA, IF, WB, IHC, IP

Recommended Dilution

WB: 1:2000-1:20000; IP: 1:1000-1:5000; IHC: 1:200-1:1000; IF: 1:20-1:500

UNIPROT INFORMATION

UniProt ID

P35222

IMAGES