anti- CD206 antibody

Explore the intricate world of macrophage biology with our Anti-CD206 Polyclonal Antibody, available in a 100µg size. CD206, also known as mannose receptor C type 1 (MRC1), is a cell surface receptor predominantly expressed on macrophages, where it plays a pivotal role in antigen uptake, immune regulation, and tissue homeostasis.

Derived from rabbit hosts, this polyclonal antibody offers exceptional sensitivity and versatility for various applications, including flow cytometry, Western blotting, and immunohistochemistry. Its polyclonal nature allows recognition of multiple epitopes, enhancing its utility in diverse research contexts.

With 100µg at your disposal, you have a generous supply for multiple experiments, reducing the need for frequent reordering and ensuring the continuity of your research.

Don't miss the opportunity to unravel the multifaceted functions of CD206 in macrophage biology and its implications in immune responses and tissue repair. With our Anti-CD206 Polyclonal Antibody, you can confidently advance your research and contribute to advancements in immunology and immunotherapeutic strategies.

Product Name

CD206 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains(responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.

IMMUNOGEN INFORMATION

Immunogen

mannose receptor, C type 1

Synonyms

CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1

Observed MW

166 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

P22897

IMAGES