anti- ATP2A2 antibody

Explore the role of ATP2A2 in cellular calcium homeostasis with our Anti-ATP2A2 Antibody, now available in a 100µg size. ATP2A2, a critical calcium pump protein, is responsible for maintaining calcium balance within cells, a process essential for muscle contraction and relaxation.

Our meticulously developed monoclonal antibody ensures unparalleled specificity and sensitivity, making it the ideal choice for a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence. It provides the precision and reliability needed for accurate results in your calcium homeostasis research.

With 100µg at your disposal, you have an ample supply for multiple experiments, minimizing interruptions and allowing you to maintain the momentum of your research.

Don't miss the opportunity to unravel the intricacies of cellular calcium regulation and the essential role of ATP2A2. With our Anti-ATP2A2 Antibody, you can confidently delve into your research and uncover the secrets hidden within this critical calcium pump protein.

Product Name

ATP2A2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.

IMMUNOGEN INFORMATION

Immunogen

ATP2A2

Synonyms

ATP2B, DAR, DD, SERCA2

Observed MW

110 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P16615

IMAGES