anti- AIF1 antibody

Unveil the secrets of immune responses and microglial activation with our cutting-edge Anti-AIF1 Antibody, now available in a convenient 100µg size.

The Anti-AIF1 Antibody, also known as Allograft Inflammatory Factor 1, is meticulously designed to meet the rigorous demands of the scientific community. AIF1 is a critical protein involved in immune cell function and has implications in neuroinflammatory disorders, making it a central focus in studies of immunology and neurology. Our antibody offers exceptional specificity and sensitivity, rendering it an ideal choice for various applications, from immunohistochemistry to flow cytometry and more.

What truly sets our Anti-AIF1 Antibody apart is its outstanding performance. Rigorously tested and validated, it ensures consistent and reproducible results, effectively reducing experimental variability and saving you valuable time and resources.

With a 100µg size, this product strikes the perfect balance between cost-effectiveness and practicality, providing an ample supply of antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-AIF1 Antibody is suitable for researchers at all levels, from novices to seasoned experts. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Empower your research with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-AIF1 Antibody at your fingertips. Step into the forefront of scientific discovery in immune regulation and neuroinflammatory processes with a dependable partner by your side. Trust in our unwavering dedication to quality and innovation as you explore the intricacies of AIF1's roles in immune cell activation and neuroinflammation.

Product Name

AIF1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

AIF1, also named as G1, IBA1 or daintain/AIF-1, is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Despite a lack of detailed knowledge on the in vivo physiological functions of AIF-1, there is growing evidence that shows its aberrant expression contributes to the pathogenesis of many autoimmune diseases, including rheumatoid arthritis. (20944424). AIF1 is an actin-binding protein that enhances membrane ruffling and RAC activation. It enhances lymphocyte migration and the actin-bundling activity of LCP1. AIF1 plays a role in RAC signaling and in phagocytosis and a role in vascular inflammation. AIF1 promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. It is also as a microglial cell marker.

IMMUNOGEN INFORMATION

Immunogen

allograft inflammatory factor 1

Synonyms

AIF 1, AIF1, G1, IBA1, IRT 1, Protein G1

Observed MW

16 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

P55008

IMAGES