anti- CLDN5 antibody

Explore the intricate world of tight junctions and endothelial barrier function with our Anti-CLDN5 Antibody, now available in a 100µg size. CLDN5 (Claudin 5) is a key component of tight junctions in endothelial cells, contributing to the formation and maintenance of the blood-brain barrier and other endothelial barriers.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of CLDN5 protein in your experiments. Researchers studying vascular biology, blood-brain barrier function, or related areas will benefit from the accuracy and reliability of this antibody.

Our high-quality Anti-CLDN5 Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Dive into the forefront of endothelial barrier research and gain valuable insights into the role of CLDN5 in regulating vascular permeability and barrier integrity.

Product Name

CLDN5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

CLDN5

Synonyms

AWAL, BEC1, CPETRL1, TMVCF

Observed MW

25 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

O00501

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