anti- XRP2 antibody

anti- XRP2 antibody

Product Name

XRP2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Acts as a GTPase-activating protein(GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119(or UNC119B). Acts as a GTPase-activating protein(GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.

IMMUNOGEN INFORMATION

Immunogen

retinitis pigmentosa 2

Synonyms

DELXp11.3, KIAA0215, Protein XRP2, RP2, TBCCD2

Observed MW

40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

O75695

IMAGES

Immunohistochemistry of paraffin-embedded human intestinal cancer using FNab09990(XRP2 antibody) at dilution of 1:100

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09990(XRP2 antibody) at dilution of 1:1000