anti- CTNNB1 antibody

The anti-CTNNB1 antibody, available in a 100µg size, is a powerful tool for researchers in the field of cell biology and molecular research. CTNNB1, also known as beta-catenin, plays a pivotal role in cell adhesion, signal transduction, and gene regulation. Dysregulation of CTNNB1 has been associated with various diseases, including cancer.

This polyclonal antibody is designed to specifically target and detect CTNNB1 in biological samples. It has been rigorously validated to ensure high specificity and sensitivity, making it ideal for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.

Our anti-CTNNB1 antibody is sourced from high-quality materials and manufactured under stringent quality control standards, ensuring reliable and reproducible results. Researchers can trust this antibody for accurate and consistent data in their experiments.

With its 100µg size, this product provides researchers with an ample supply to support multiple experiments. It is compatible with various sample types, including cell lysates and tissue sections. Whether investigating cellular adhesion, Wnt signaling pathways, or cancer-related studies, this antibody is an indispensable tool for your research endeavors.

Advance your scientific investigations with confidence using the anti-CTNNB1 antibody, backed by our commitment to quality and excellence in molecular biology research.

Product Name

CTNNB1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

catenin(cadherin-associated protein), beta 1, 88kDa

Synonyms

b cat, Beta catenin, beta-Catenin, Catenin beta 1, CTNNB, CTNNB1, PRO2286, β catenin, β-catenin

Observed MW

90 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P35222

IMAGES

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab09998(CTNNB1 Antibody) at dilution of 1:200

mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab09998(CTNNB1 antibody) at dilution of 1:1000