anti- CD3 epsilon antibody

Delve into the intricate world of immune signaling with our Anti-CD3 Epsilon Polyclonal Antibody, available in a convenient 100µg size. CD3 Epsilon, a subunit of the CD3 complex, is a crucial component of the T-cell receptor (TCR) complex, essential for T-cell activation and regulation of immune responses.

Our meticulously developed polyclonal antibody, derived from rabbit hosts, offers exceptional sensitivity and versatility for various research applications. Whether you're delving into flow cytometry, Western blotting, or immunohistochemistry, this antibody's polyclonal nature allows recognition of multiple epitopes, enhancing its utility in diverse research contexts.

With 100µg at your disposal, you have a generous supply for multiple experiments, reducing the need for frequent reordering and ensuring the continuity of your research.

Explore the multifaceted functions of CD3 Epsilon in T-cell activation, immune response regulation, and its implications in autoimmune diseases and immunotherapies. Our Anti-CD3 Epsilon Polyclonal Antibody empowers you to confidently investigate CD3 Epsilon-related research, shedding light on crucial mechanisms of immune regulation and paving the way for advancements in immunology and targeted therapies.

Whether you're an experienced researcher or just beginning your journey into the fascinating world of CD3 Epsilon, our antibody provides the precision, reliability, and quantity you need to drive your investigations forward. Unlock the secrets of CD3 Epsilon and its pivotal role in immune responses with this powerful research tool.

Product Name

CD3 epsilon antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells.

IMMUNOGEN INFORMATION

Immunogen

CD3e molecule, epsilon (CD3-TCR complex)

Synonyms

CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE

Observed MW

23-25 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500 - 1:2000

UNIPROT INFORMATION

UniProt ID

P07766

IMAGES

various lysates were subjected to SDS PAGE followed by western blot with FNab10016( CD3E Antibody) at dilution of 1:1000