anti- Endoglin/CD105 antibody

Unlock the secrets of endothelial cell function with our high-quality anti-Endoglin/CD105 antibody. Endoglin, a crucial player in angiogenesis and vascular biology, can be explored extensively with 100µg of this polyclonal antibody.

Investigate how Endoglin influences endothelial cell activation, angiogenic pathways, and its significance in cardiovascular health and disease. Our antibody is meticulously designed to deliver precise and reliable results, making it suitable for various applications, from basic research to diagnostics and drug development.

Trust in our commitment to quality and accuracy as you decode the roles of Endoglin/CD105 in vascular biology and its impact on human health.

Product Name

Endoglin/CD105 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

endoglin

Synonyms

CD105, END, Endoglin, ENG, FLJ41744, HHT1, ORW, ORW1

Observed MW

50 kDa, 67 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

P17813

IMAGES

MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab10035(ENG antibody) at dilution of 1:1000