anti- KLF4 antibody

anti- KLF4 antibody

­ Product Name

KLF4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.

IMMUNOGEN INFORMATION

Immunogen

Kruppel-like factor 4 (gut)

Synonyms

EZF, GKLF, KLF4

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

O43474

IMAGES

Immunohistochemistry of paraffin-embedded rat kidney using FNab10038(KLF4 antibody) at dilution of 1:100

HeLa cells were subjected to SDS PAGE followed by western blot with FNab10038(KLF4 antibody) at dilution of 1:1000