anti- SKP1 antibody

anti- SKP1 antibody

Product Name

SKP1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

IMMUNOGEN INFORMATION

Immunogen

S-phase kinase-associated protein 1

Synonyms

EMC19, OCP2, SKP1A, TCEB1L

Observed MW

19 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P63208

IMAGES

Immunohistochemistry of paraffin-embedded rat testis using FNab10039(SKP1 antibody) at dilution of 1:100

A549 cells were subjected to SDS PAGE followed by western blot with FNab10039(SKP1 antibody) at dilution of 1:1000