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Immunohistochemistry of paraffin-embedded rat testis tissue slide using FNab10082( KPCA Antibody) at dilution of 1:200 -
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab10082(KPCA antibody) at dilution of 1:1000
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SKU:FNab10082
anti- KPCA antibody
anti- KPCA antibody
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Product Name
KPCA antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
BACKGROUND
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
IMMUNOGEN INFORMATION
Immunogen
protein kinase C, alpha
Synonyms
AAG6, PKC A, PKC alpha, PKCA, PRKACA, PRKCA, Protein kinase C alpha type, protein kinase C, alpha
Observed MW
77 kDa
APPLICATION
Tested Application
ELISA, WB, IHC, IF
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
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