anti- CD44 antibody

Embark on a journey into the realm of cell adhesion, migration, and signaling with our Anti-CD44 Polyclonal Antibody, now available in a convenient 100µg size. CD44, a multifunctional cell surface glycoprotein, is involved in numerous cellular processes, including cell adhesion, migration, lymphocyte activation, and tumor metastasis.

Our meticulously developed polyclonal antibody, derived from rabbit hosts, offers exceptional sensitivity and versatility for various research applications. Whether you're studying CD44-mediated cell adhesion or investigating its role in cancer progression, this antibody's polyclonal nature allows recognition of multiple epitopes, enhancing its utility in diverse research contexts.

With 100µg at your disposal, you have a generous supply for multiple experiments, reducing the need for frequent reordering and ensuring the continuity of your research.

Explore the intricate mechanisms by which CD44 regulates cell adhesion dynamics, extracellular matrix interaction, and its role in cancer metastasis. Investigate the molecular intricacies of CD44-mediated processes, advancing our understanding of cell biology and potential therapeutic interventions.

Product Name

CD44 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

IMMUNOGEN INFORMATION

Immunogen

CD44 molecule

Synonyms

LHR, MDU2, MDU3, MIC4

Observed MW

79 kDa

APPLICATION

Tested Application

ELISA, IHC

Recommended Dilution

IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P16070

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