anti- CASP7 antibody

anti- CASP7 antibodyOur Anti-CASP9 Polyclonal Antibody is an essential tool for researchers exploring apoptosis, a highly regulated process crucial for maintaining tissue homeostasis and eliminating damaged cells. Caspase-9 (CASP9) is a pivotal enzyme in the apoptotic cascade, serving as an initiator caspase that plays a central role in apoptosome formation and activation.

This polyclonal antibody is meticulously designed to provide high specificity and sensitivity in detecting CASP9, making it an ideal choice for various experimental applications, including Western blotting, immunohistochemistry, and immunoprecipitation. Its polyclonal nature ensures recognition of multiple epitopes, enhancing the reliability of your results.

With a generous 100µg vial size, you'll have an ample supply of this high-quality antibody to support multiple experiments, ensuring cost-effectiveness and consistent data. Investigate the intricate mechanisms of apoptosis and CASP9's pivotal role in regulating programmed cell death with confidence, knowing you have a trusted research partner in this polyclonal antibody.

Our CASP9 Polyclonal Antibody is rigorously validated to provide dependable and reproducible results, empowering your research into apoptosis, cancer biology, and various disease states influenced by aberrant cell death pathways. Advance your scientific endeavors with this versatile and reliable antibody, confident in its ability to contribute to groundbreaking discoveries in the field of cell biology.

Product Name

CASP7 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

IMMUNOGEN INFORMATION

Immunogen

caspase-7

Synonyms

CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3

Observed MW

37kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P55210

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