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FineTest

SKU:FNab10129

anti- 4EBP1 antibody

anti- 4EBP1 antibody

Regular price $330.00 USD
Regular price Sale price $330.00 USD
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Accelerate your molecular biology research with our Anti-4EBP1 Antibody, available in a convenient 100µg size. This high-quality antibody is meticulously designed to target 4EBP1, a key protein in the mTOR signaling pathway that plays a central role in protein translation regulation.

Our Anti-4EBP1 Antibody offers exceptional specificity and sensitivity, allowing you to confidently explore the intricate mechanisms of protein synthesis control. This antibody is invaluable for investigating the role of 4EBP1 in cell growth, cancer, and neurological disorders, as well as for developing potential therapeutic strategies.

With 100µg of this antibody at your disposal, you have ample supply for multiple experiments, reducing the need for frequent reorders and ensuring uninterrupted progress in your research. Each batch of our antibody undergoes rigorous quality control measures to guarantee consistent performance and reliability in your experiments.

Whether you're studying translational control, investigating the effects of mTOR inhibitors, or exploring the signaling pathways in various diseases, our Anti-4EBP1 Antibody empowers you to delve deeper into the molecular mechanisms that underlie these processes. Order your supply today and join leading researchers who rely on our high-quality antibodies for their critical work.

Product Name

4EBP1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 4E binding protein 1

Synonyms

4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I

Observed MW

17 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

Q13541

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab10129(4EBP1 Antibody) at dilution of 1:50
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab10129(4EBP1 antibody) at dilution of 1:1000
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