anti- CD16 antibody

Explore the multifaceted roles of CD16, also known as FcγRIII, in immune effector cell function with our Anti-CD16 Polyclonal Antibody, available in a 100µg size. CD16 is a cell surface receptor expressed on natural killer (NK) cells, neutrophils, and macrophages, where it plays a pivotal role in antibody-dependent cellular cytotoxicity (ADCC) and immune regulation.

Derived from rabbit hosts, this polyclonal antibody offers exceptional sensitivity and versatility for various applications, including flow cytometry, Western blotting, and immunohistochemistry. Its polyclonal nature allows recognition of multiple epitopes, enhancing its utility in diverse research contexts.

With 100µg at your disposal, you have a generous supply for multiple experiments, reducing the need for frequent reordering and ensuring the continuity of your research.

Don't miss the opportunity to delve into the intricate functions of CD16 in immune effector cell function. With our Anti-CD16 Polyclonal Antibody, you can confidently advance your research and contribute to advancements in immunology and immune cell biology.

Product Name

CD16 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B.

IMMUNOGEN INFORMATION

Immunogen

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

Synonyms

CD16, CD16A, CD16a antigen, Fc gamma RIII, Fc gamma RIII alpha, Fc gamma RIIIa, FCG3, FCGR3, FCGR3A, FCGRIII, FCR 10, FCRIII, FCRIIIA, IGFR3, IgG Fc receptor III 2

Observed MW

55 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

P08637

IMAGES