anti- EGFR antibody

Embark on a journey of investigation into Epidermal Growth Factor Receptor (EGFR) signaling with our highly specific Monoclonal Anti-EGFR Antibody, now available in a 100µg size. EGFR, a transmembrane receptor, plays a pivotal role in cell growth, proliferation, and differentiation.

This monoclonal antibody is meticulously validated for specificity, ensuring that your research on EGFR signaling, receptor activation, and its implications in cancer and other diseases is backed by a reliable tool.

EGFR's significance in cellular signaling, particularly in cancer biology, has made it a subject of intense research interest. Whether your research focuses on receptor signaling, targeted therapies, or the molecular mechanisms underlying diseases, this monoclonal antibody is an indispensable addition to your toolkit.

Order your 100µg vial today and embark on an exploration of EGFR signaling pathways and their roles in diverse biological processes.

Product Name

EGFR antibody

Size

100µg

Form

liquid

Purification

protein A+G purified

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

IMMUNOGEN INFORMATION

Immunogen

epidermal growth factor receptor

Synonyms

EGFR, ERBB, ERBB1, HER1, mENA, PIG61, Proto oncogene c ErbB 1

Observed MW

140-160 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:2000 - 1:10000; IHC: 1:100 - 1:1000

UNIPROT INFORMATION

UniProt ID

P00533

IMAGES