anti- TRADD antibody

Dive into the world of tumor necrosis factor receptor-associated death domain protein (TRADD) with our Anti-TRADD Antibody. This high-quality antibody, available in a 100µg size, offers specificity and sensitivity for precise protein detection. Key Features: Specific Targeting: The Anti-TRADD Antibody is rigorously validated to specifically recognize TRADD, ensuring accurate results in your studies of cell death signaling and immune responses. Versatile Applications: Compatible with a variety of research techniques, including Western blotting, immunoprecipitation, and immunofluorescence. It's an ideal choice for studies in immunology, cell signaling, and apoptosis research. High Sensitivity: This antibody is optimized for superior sensitivity, allowing you to detect low-abundance TRADD in complex biological samples, enabling a deeper understanding of signaling pathways. Broad Research Applications: From unraveling the complexities of immune regulation to investigating apoptosis, this antibody is an essential tool for researchers exploring cell death signaling and immune response mechanisms. Incorporate the Anti-TRADD Antibody into your research to gain deeper insights into the role of TRADD in cellular responses and immune regulation. With its precision and reliability, it's a valuable asset for scientists and researchers in diverse fields.

Product Name

TRADD antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A(By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

IMMUNOGEN INFORMATION

Immunogen

TNFRSF1A-associated via death domain

Synonyms

Hs.89862, TRADD

Observed MW

34 kDa, 27 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200 - 1:2000; IHC: 1:50 - 1:500

UNIPROT INFORMATION

UniProt ID

Q15628

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