anti- TBP antibody

Our Anti-TBP Antibody is your gateway to unraveling the mysteries of transcription with precision and accuracy. Available in a 100µg size, this antibody is designed to specifically detect the TATA-binding protein (TBP), a core component of the transcription factor IID (TFIID) complex. Here are the key features: Key Features of the TBP Antibody: Target-Specific Precision: Meticulously validated to recognize TBP, ensuring accurate results without cross-reactivity with other proteins. This precision is essential for transcription research. Versatile Applications: Compatible with a wide range of research techniques, including chromatin immunoprecipitation (ChIP), immunofluorescence, and Western blotting. Ideal for studies in gene regulation, transcriptional initiation, and chromatin dynamics. High Sensitivity: The Anti-TBP Antibody is optimized for sensitivity, enabling the detection of low-abundance TBP in complex biological samples. This is especially crucial for capturing subtle changes in TBP levels. Broad Research Applications: From understanding the fundamentals of gene expression to deciphering regulatory mechanisms, this antibody is a valuable tool for transcription, molecular biology, and gene regulation studies. Incorporate the Anti-TBP Antibody into your research to unlock the intricacies of transcription, gene regulation, and the fundamental processes that govern cellular activities. Its specificity and reliability make it an indispensable asset for researchers across various disciplines.

Product Name

TBP antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex(PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

IMMUNOGEN INFORMATION

Immunogen

TATA box binding protein

Synonyms

GTF2D1, TF2D, TFIID

Observed MW

37-43kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P20226

IMAGES