anti- GP repeat antibody

GP repeat antibody

Product Name

GP repeat antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The C9orf72 "GGGGCC" repeat sequence codes five repeat peptide "GA repeat; GAGAGAGAGA", "GP repeat; GPGPGPGPG", "GR repeat; GRGRGRGRG", "AP repeat; APAPAPAPA" and "PR repeat; PRPRPRPRP". It was described previously that aggregated forms of poly-GA and poly-GP proteins do not enter the separation gel (PMID: 26374446). This antibody is used to detect the GP repeated sequence. The recombinant protein with 6*His tag or GST tag which contains the sequence “GPGPGPGPG” were used to detect this antibody.

IMMUNOGEN INFORMATION

Immunogen

GP repeat

Synonyms

C9RAN, GGGCC, GP repeat, GPGPGPGP, poly GP, poly PG

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

IMAGES

Immunohistochemistry of paraffin-embedded human bain using FNab03570(GP repeat antibody) at dilution of 1:100

Recombinant proteins which contains GP repeat sequence were subjected to SDS PAGE followed by western blot with FNab03570(GP repeat Antibody) at dilution of 1:1000