anti- SMG5 antibody

anti- SMG5 antibody

Product Name

SMG5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A(PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.

IMMUNOGEN INFORMATION

Immunogen

Smg-5 homolog, nonsense mediated mRNA decay factor

Synonyms

EST1 like protein B, EST1B, hSMG 5, KIAA1089, LPTS interacting protein, LPTS RP1, LPTSRP1, Protein SMG5, RP11 54H19.7, SMG 5, SMG 5 homolog, SMG5

Observed MW

114 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9UPR3

IMAGES

HeLa cells were subjected to SDS PAGE followed by western blot with FNab08025(SMG5 antibody) at dilution of 1:600