anti- SMCR7L antibody

anti- SMCR7L antibody

Product Name

SMCR7L antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa(also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.

IMMUNOGEN INFORMATION

Immunogen

Smith-Magenis syndrome chromosome region, candidate 7-like

Synonyms

dJ1104E15.3, FLJ20232, HSU79252, MID51, MIEF1, SMCR7L

Observed MW

49 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IP

Recommended Dilution

WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q9NQG6

IMAGES