anti- SMYD3 antibody

anti- SMYD3 antibody

Product Name

SMYD3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di-and tri-methylation, but not monomethylation(PubMed:15235609, PubMed:22419068). Also methylates 'Lys-5' of histone H4(PubMed:22419068). Plays an important role in transcriptional activation as a member of an RNA polymerase complex(PubMed:15235609). Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences(PubMed:15235609).

IMMUNOGEN INFORMATION

Immunogen

SET and MYND domain containing 3

Synonyms

ZMYND1, ZNFN3A1

Observed MW

42-45 kDa

APPLICATION

Tested Application

ELISA, IHC, IP, WB

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9H7B4

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer using FNab08049(SMYD3 antibody) at dilution of 1:50

IP Result of anti-SMYD3 (IP:FNab08049, 4ug; Detection:FNab08049 1:500) with COLO 320 cells lysate 1280ug.

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08049(SMYD3 antibody) at dilution of 1:800