anti- SNCB antibody

anti- SNCB antibody

Product Name

SNCB antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine(6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

IMMUNOGEN INFORMATION

Immunogen

synuclein, beta

Synonyms

Beta synuclein, SNCB, synuclein, beta, SYUB

Observed MW

14-18 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, FC

Recommended Dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:10-1:100; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q16143

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer using FNab08062(SNCB antibody) at dilution of 1:10

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08062(SNCB antibody) at dilution of 1:600