anti- SOD1 antibody

anti- SOD1 antibody

Product Name

SOD1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1(adult))(SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.

IMMUNOGEN INFORMATION

Immunogen

superoxide dismutase 1, soluble

Synonyms

Superoxide dismutase [Cu-Zn],Superoxide dismutase 1,

hSod1

Observed MW

16 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP, IF

Recommended Dilution

WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:100-1:400; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

P00441

IMAGES

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab08103(SOD1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

IP Result of anti-SOD1 (IP:FNab08103, 3ug; Detection:FNab08103 1:1500) with HEK-293 cells lysate 1000ug.

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08103(SOD1 antibody) at dilution of 1:1500