anti- SOX2 antibody

anti- SOX2 antibody

Product Name

SOX2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206(By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal(By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation(By similarity).

IMMUNOGEN INFORMATION

Immunogen

SRY(sex determining region Y)-box 2

Synonyms

ANOP3, MCOPS3, SOX2, Transcription factor SOX 2

Observed MW

34kd

APPLICATION

Tested Application

ELISA, IF, WB, IHC

Recommended Dilution

WB: 1:2000-1:20000; IHC: 1:50-1:200; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P48431

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer tissue using FNab08125(SOX2 Antibody) at dilution of 1:100

Immunofluorescent analysis of ( 4% PFA ) fixed mouse embryo tissue using FNab08125 ( SOX2 Antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)

U-251 cells were subjected to SDS PAGE followed by western blot with FNab08125(SOX2 antibody) at dilution of 1:5000