anti- SPARC antibody

anti- SPARC antibody

Product Name

SPARC antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

secreted protein, acidic, cysteine-rich (osteonectin)

Synonyms

ON

Observed MW

35 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P09486

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer using FNab08153(SPARC antibody) at dilution of 1:100

human placenta tissue were subjected to SDS PAGE followed by western blot with FNab08153(SPARC antibody) at dilution of 1:1000