anti- SPPL2A antibody

anti- SPPL2A antibody

Product Name

SPPL2A antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

SPPL2A(Signal peptide peptidase-like 2A) is also named as IMP3(Intramembrane protease 3), PSL2(Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A(SPPL2a) is localised in lysosomes/late endosomes(PMID:21896273).

IMMUNOGEN INFORMATION

Immunogen

signal peptide peptidase-like 2A

Observed MW

58 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8TCT8

IMAGES

Immunohistochemistry of paraffin-embedded human testis using FNab08191(SPPL2A antibody) at dilution of 1:50

human colon tissue were subjected to SDS PAGE followed by western blot with FNab08191(SPPL2A antibody) at dilution of 1:500