anti- SPTBN1-Specific antibody

anti- SPTBN1-Specific antibody

Product Name

SPTBN1-Specific antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

SPTBN1 is the non-erythrocytic form of β-spectrin or β-fodrin. Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. Reduced expression of SPTBN1 has been found to correlate with shorter survival of patients with hepatocellular cancer, pancreatic cancer and other malignancies of the gastrointestinal tract, suggesting tumor suppression ability of this protein.

IMMUNOGEN INFORMATION

Immunogen

spectrin, beta, non-erythrocytic 1

Synonyms

Beta II spectrin, beta-fodrin, betaSpII, ELF, Fodrin beta chain, Spectrin beta chain, brain 1, SPTB2, SPTBN1

Observed MW

275 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:5000; IP:1:200-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q01082

IMAGES

Immunohistochemistry of paraffin-embedded human lung using FNab08204(SPTBN1-Specific antibody) at dilution of 1:100

IP Result of anti-SPTBN1-Specific (IP:FNab08204, 5ug; Detection:FNab08204 1:600) with HEK-293 cells lysate 1000ug.

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08204(SPTBN1-Specific antibody) at dilution of 1:300