anti- SSB antibody

anti- SSB antibody

Product Name

SSB antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.

IMMUNOGEN INFORMATION

Immunogen

Sjogren syndrome antigen B (autoantigen La)

Observed MW

47 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:1000; IHC: 1:100 - 1:200

UNIPROT INFORMATION

UniProt ID

P05455

IMAGES

Immunohistochemistry of paraffin-embedded human colon cancer using FNab08246(SSB antibody) at dilution of 1:50

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08246( SSB Antibody) at dilution of 1:1000