anti- STEAP3 antibody

anti- STEAP3 antibody

Product Name

STEAP3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

IMMUNOGEN INFORMATION

Immunogen

STEAP family member 3

Synonyms

TSAP6

Observed MW

55 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q658P3

IMAGES

Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab08318(STEAP3 Antibody) at dilution of 1:50

IP Result of anti-STEAP3 (IP:FNab08318, 4ug; Detection:FNab08318 1:700) with C6 cells lysate 1000ug.

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab08318(STEAP3 antibody) at dilution of 1:2000