anti- TMEM16A/DOG1 antibody

Product Name

TMEM16A/DOG1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ANO1 also named as DOG1, ORAOV2, TAOS2 and TMEM16A, acts as a calcium-activated chloride channel. It is required for normal tracheal development. ANO1(or DOG1) is used as an aid in the identification and diagnosis of gastrointestinal stromal tumors(GIST) within the context of an antibody panel, the patient’s clinical history, and other diagnostic tests evaluated by a qualified pathologist. The immunogen is the C-terminal of ANO1. This antibody can recognize isoform1 and isoform2 of human ANO1.

IMMUNOGEN INFORMATION

Immunogen

Transmembrane protein 16A

Synonyms

ANO1, Anoctamin 1, DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A, TMEM16A/DOG1, Transmembrane protein 16A

APPLICATION

Tested Application

ELISA, IHC

Recommended Dilution

IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q5XXA6

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