anti- TRPV5 antibody

Product Name

TRPV5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine(PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules(By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification(PubMed:11549322, PubMed:18768590). A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay(By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating(By similarity).

IMMUNOGEN INFORMATION

Immunogen

transient receptor potential cation channel, subfamily V, member 5

Synonyms

Calcium transport protein 2, CAT2, ECaC, ECAC1, Epithelial calcium channel 1, Osm 9 like TRP channel 3, OTRPC3, TRPV5

Observed MW

43 kDa

APPLICATION

Tested Application

ELISA, IF

Recommended Dilution

IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q9NQA5