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Immunohistochemistry of paraffin-embedded human pancreas tissue slide using FNab09209(UBR2 Antibody) at dilution of 1:50 -
BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab09209(UBR2 antibody) at dilution of 1:600
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FineTest
SKU:FNab09209
anti- UBR2 antibody
anti- UBR2 antibody
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$280.00 USD
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Product Name
UBR2 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
IMMUNOGEN INFORMATION
Immunogen
ubiquitin protein ligase E3 component n-recognin 2
Synonyms
BA49A4.1, C6orf133, dJ242G1.1, dJ392M17.3, DKFZp686C08114, KIAA0349, N recognin 2, RP3 392M17.3, UBR2
Observed MW
66 kDa
APPLICATION
Tested Application
ELISA, WB, IF, IHC
Recommended Dilution
WB: 1:200-1:2000; IF：1：10-1:100; IHC: 1:20-1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
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