anti- UCHL1/PGP9.5 antibody

Product Name

UCHL1/PGP9.5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm(PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene(PMID:15048890).

IMMUNOGEN INFORMATION

Immunogen

ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase)

Synonyms

Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uch L1, UCHL1

Observed MW

26 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:5000; IHC：1:100-1:500; IP: 1:1000-1:5000

UNIPROT INFORMATION

UniProt ID

P09936

IMAGES