anti- USP49 antibody

Product Name

USP49 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Specifically deubiquitinates histone H2B at 'Lys-120'(H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.

IMMUNOGEN INFORMATION

Immunogen

ubiquitin specific peptidase 49

Synonyms

Deubiquitinating enzyme 49, Ubiquitin thiolesterase 49, USP49

Observed MW

73 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IHC: 1：20-1：200

UNIPROT INFORMATION

UniProt ID

Q70CQ1

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